Brugada Syndrome Medical Slides
Generate publication-quality brugada syndrome lecture slides in 30 seconds. AI-powered content structured for clinical education.
Generate Brugada Syndrome DeckWhy teach Brugada Syndrome?
Brugada syndrome is a genetic arrhythmia disorder (SCN5A mutations in 20-30% of cases) characterized by distinctive ST elevation in right precordial leads and a risk of ventricular fibrillation and sudden death, particularly during rest or sleep. It accounts for 4-12% of all sudden cardiac deaths and up to 20% of sudden death in structurally normal hearts. The 2022 HRS/EHRA/APHRS/LAHRS expert consensus refined the diagnostic criteria and risk stratification approach.
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Brugada Syndrome Presentation FAQ
How should the Type 1 versus Type 2 ECG pattern be taught?
Show side-by-side ECGs: Type 1 (coved) shows ≥2 mm J-point elevation with gradual descending ST segment leading directly into inverted T wave in ≥1 right precordial lead (V1-V2) — this is the only diagnostic pattern. Type 2 (saddleback) has ≥0.5 mm J-point elevation with positive or biphasic T wave and is suggestive but non-diagnostic, requiring sodium channel blocker provocation test to unmask Type 1.
Why is fever important to address in Brugada teaching?
Fever is a well-documented trigger for Type 1 Brugada pattern unmasking and ventricular arrhythmias because elevated temperature further impairs sodium channel function in SCN5A mutation carriers. Teach that aggressive antipyretic therapy (acetaminophen, cooling measures) is essential, and that febrile illness accounts for a significant proportion of Brugada-related cardiac events. Patients should carry alert cards and avoid temperatures >38.5°C.
How should the ICD decision for asymptomatic Brugada patients be framed?
Present the controversy: ICD is Class I for cardiac arrest survivors and Class IIa for spontaneous Type 1 ECG with syncope history. For asymptomatic patients with spontaneous Type 1, the 2022 expert consensus recommends EP study with programmed stimulation, but its predictive value is debated. Discuss the ongoing BRUGADA-ICD registry data showing annual event rates of 0.5% in asymptomatic patients versus the 5% long-term ICD complication rate, framing this as a genuine shared decision-making scenario.
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