Multiple Sclerosis Medical Slides
Generate publication-quality multiple sclerosis lecture slides in 30 seconds. AI-powered content structured for clinical education.
Generate Multiple Sclerosis DeckWhy teach Multiple Sclerosis?
Multiple sclerosis affects approximately 2.8 million people worldwide, with peak onset in young adults aged 20-40 years. The 2017 revised McDonald criteria enable earlier diagnosis, and the treatment landscape now includes over 20 disease-modifying therapies spanning injectable, oral, and infusion platforms. Teaching MS requires understanding of diagnostic criteria, relapse management, DMT selection strategies (escalation vs high-efficacy first), and progressive disease management.
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Multiple Sclerosis Presentation FAQ
How should the escalation versus high-efficacy-first DMT debate be presented?
Present both strategies with evidence: traditional escalation starts with moderate-efficacy drugs (interferons, glatiramer, dimethyl fumarate) and escalates after breakthrough activity. The emerging treat-to-target approach starts with high-efficacy therapies (natalizumab, ocrelizumab, alemtuzumab) early, supported by retrospective data showing less disability accumulation. Reference the TREAT-MS and DELIVER-MS trials comparing these approaches prospectively.
What MRI teaching points are essential for MS diagnosis slides?
Show characteristic lesion locations meeting DIS criteria: ≥1 T2 lesion in at least 2 of 4 regions (periventricular, cortical/juxtacortical, infratentorial, spinal cord). Demonstrate DIT with simultaneous gadolinium-enhancing and non-enhancing lesions or new T2 lesions on follow-up. Teach the "central vein sign" on 3T MRI as an emerging biomarker differentiating MS from microvascular disease.
How should relapse versus pseudo-relapse be distinguished in teaching?
Define a true relapse as new or worsening neurological symptoms lasting >24 hours in the absence of fever or infection (Uhthoff phenomenon). Pseudo-relapses are reactivation of prior symptoms triggered by infection, heat, stress, or fatigue. Teach the workup: urinalysis, CBC, and temperature check before treating with IV methylprednisolone 1g daily for 3-5 days. PLEX is reserved for steroid-refractory severe relapses affecting ambulation or vision.
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